1/29/2024 0 Comments Fibrous obliteration of appendixThese findings are similar to the neural proliferation of central obliterative appendiceal neuroma. The second type is described as an intramucosal pattern. ![]() There is an extensive capillary network throughout each appendiceal neuroma. The proliferation of the lumen consists of fibrous tissue that rests on the submucosa. The lesion consists of loosely arranged aggregates of spindle cells in a background network of eosinophilic cell processes. This type of neuroma occurs most commonly. A central obliterative appendiceal neuroma has a fibromyxoid core with patchy chronic inflammation and lymphoid aggregates. There are three microscopic histologie patterns for neuroma. The patient’s pain slowly decreased and she was discharged to home three days after the exploratory laporoscopy with removal of the appendix.īased on the literature review of appendiceal neuroma, it seems that this finding is a rare histologie finding. These findings were consistent with a diagnosis of appendiceal neuroma. Nerve fibers and ganglion cells were also noted. There were spindle cells noted to be within a myxoid background. The microscopic description showed fibrous obliteration of the appendiceal lumen. There were no inflammatory changes found on the microscopic report. When the appendix was sectioned, it was noted to have a very narrow lumen grossly. The appendix measured 3.5 cm in length and 0.4 cm in diameter. Although there was no apparent evidence of pathology of the appendix, it was removed. ![]() Laparoscopy was performed for persistent symptoms, and thorough inspection of suspected etiologies disclosed no abnormalities. Abdominal ultrasound and computerized tomographic scan were normal. Laboratory studies were normal and a presumptive diagnosis of a viral illness was made. She was afebrile and other positive findings were absent. Physical exam showed localized peritoneal irritation in the right lower quadrant. Her last menstrual period was one week before presentation. Case ReportĪ 43-year-old woman presented with a four-day history of right lower quadrant abdominal pain, generalized malaise, and anorexia. Inflamm Bowel Dis 2010 16:1093-1094.By Rhoades, Torre Lohr, Joann Jennings, MarkĪLTHOUGH THERE ARE SEVERAL benign appendiceal tumors, there is no clinical significance of benign tumors except when they cause obstruction of the appendiceal lumen and lead to acute appendicitis.1 We report a patient presenting with symptoms of acute appendicitis perhaps caused by an appendiceal neuroma. Crohn's disease patient with right lower quadrant abdominal pain for 20 years due to an appendiceal neuroma (Fibrous obliteration of the appendix). The appendix in inflammatory bowel disease in children. Miscellaneous conditions of the appendix. Unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis. Yilmaz M, Akbulut S, Kutluturk K, Sahin N, Arabaci E, Ara C, Yilmaz S. ![]() Schmutzer KJ, Bayar M, Zaki AE, Regan JF, Poletti JB. Appendiceal neuroma: report of an elusive neuroma. “Extraepithelial enterochromaffin cell-nerve fibre complexes” in the normal human appendix, and in neurogenic appendicopathy. A light-microscopic, immunohistochemical and electron-microscopic study of 20 cases. Stanley MW, Cherwitz D, Hagen K, Snover DC. WHO Classification of tumours of the digestive system, Volume 3, 4th edn. FU Med Biol 2014 16: 104-105.īosman FT, Carneiro F, Hruban RH, Theise ND. Radojković MD, Veličković L, Stevanović G.
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